Have you turned Secure Boot off? TLXOS does not support Secure Boot.
There are some other known issues - we'd argue they are BIOS bugs - with certain UEFI BIOSes. Known offenders include Dell Optiplex models, some older HP/Compaq laptops, Intel Compute Sticks, and certain NUC models (mainly the more recent ones, plus the notoriously buggy DE3815TYKHE). Issues and possible workarounds may include:
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